Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851693 | 0.80 | ALDH1A1 (0.54) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL23850602 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL31588198 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL23851042 | 0.75 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL23851040 | 0.75 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL31588171 | 0.75 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL23851407 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL23851405 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL23850803 | 0.73 | LMNA (0.65) | ALDH1A1LMNAKDM4EPKMMAPT | |
| SCHEMBL23850683 | 0.73 | LMNA (0.65) | ALDH1A1LMNAKDM4EPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113056305-A | Compound (I) | 格雷沃尔夫治疗有限公司 | 2021-06-29 | — | — | CN | disclosed |