Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893556 | 0.98 | KEAP1 (0.41) | KEAP1NFE2L2KDM4EMEN1KMT2A | |
| SCHEMBL28614328 | 0.86 | KEAP1 (0.39) | KEAP1NFE2L2KDM4EALDH1A1TDP1 | |
| SCHEMBL21819488 | 0.84 | KEAP1 (0.40) | KEAP1NFE2L2KDM4EALDH1A1TDP1 | |
| SCHEMBL21819486 | 0.84 | KEAP1 (0.40) | KEAP1NFE2L2KDM4EALDH1A1TDP1 | |
| Potassium SCHEMBL31133386 | 0.83 | KEAP1 (0.39) | KEAP1NFE2L2KDM4EALDH1A1TDP1 | |
| Potassium Ion SCHEMBL21819138 | 0.83 | HSD11B1 (0.33) | HSD17B10ALDH1A1SMN1; SMN2HSD11B1 | |
| Potassium Ion SCHEMBL21819140 | 0.83 | HSD11B1 (0.33) | HSD17B10ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL3678140 | 0.78 | NFE2L2 (0.58) | KEAP1NFE2L2KDM4EMEN1KMT2A | |
| SCHEMBL28621366 | 0.77 | KEAP1 (0.50) | KEAP1NFE2L2MEN1KMT2AUSP2 | |
| SCHEMBL21893929 | 0.75 | KEAP1 (0.51) | KEAP1NFE2L2MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |