SCHEMBL28623487

SCHEMBL28623487

O=P(Cc1cccc(Cl)c1)(Oc1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.48
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
NR4A2 P43354 1/20 0.42
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
CYP3A4 P08684 2/20 0.39
IDO1 P14902 2/20 0.39
AGXT P21549 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PGR P06401 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1967085 0.84 L3MBTL1 (0.53) HTTCYP2C19MEN1KMT2AL3MBTL1
SCHEMBL28162378 0.72 L3MBTL1 (0.41) HTTMEN1KMT2AL3MBTL1TDP1
SCHEMBL10948419 0.72 L3MBTL1 (0.55) HTTCYP2C9CYP2C19MEN1KMT2A
SCHEMBL28451418 0.71 CYP3A4 (0.50) MEN1KMT2ANR4A2RXRARXRB
SCHEMBL28621703 0.71 L3MBTL1 (0.53) HTTMEN1KMT2AL3MBTL1TDP1
SCHEMBL4247569 0.69 L3MBTL1 (0.61) HTTMEN1KMT2AL3MBTL1TDP1
SCHEMBL3424552 0.69 PGK1 (0.59) PNMT
SCHEMBL28625995 0.68 L3MBTL1 (0.50) HTTCYP2C9CYP2C19MEN1KMT2A
SCHEMBL10521264 0.68 SIGMAR1 (0.42) SIGMAR1CYP3A4IDO1AGXTPNMT
SCHEMBL11959143 0.67 MAOB (0.72) CYP1A2CYP2D6CYP2C9CYP2C19NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372383-B Preparation method of organic phosphate compound 中南大学 2022-08-02 CN disclosed
CN-113372383-A Preparation method of organic phosphate compound 中南大学 2021-09-10 CN disclosed