Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618955 | 0.89 | AKR1C3 (0.37) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20782378 | 0.89 | MAPT (0.44) | MAPTKDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL20768139 | 0.88 | KDM4E (0.39) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19464265 | 0.86 | KDM4E (0.49) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28620031 | 0.84 | DCLRE1B (0.43) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28623625 | 0.81 | MAPT (0.34) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28623585 | 0.80 | DHODH (0.38) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22280894 | 0.76 | KDM4E (0.57) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19492666 | 0.76 | MAPT (0.38) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL19464076 | 0.76 | ALDH1A1 (0.47) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |