Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614008 | 0.91 | BRAF (0.47) | SRCBRAFKDRSMN1; SMN2NPC1 | |
| SCHEMBL28631644 | 0.84 | CHEK1 (0.38) | SRCKDRTUBB4ATUBBTUBA3C | |
| SCHEMBL28616410 | 0.83 | RIPK2 (0.40) | SRCKDRSMN1; SMN2HPGDMEN1 | |
| SCHEMBL28616736 | 0.82 | SRC (0.60) | PTGS2SRCBRAFKDRSMN1; SMN2 | |
| SCHEMBL28624711 | 0.78 | PTGS2 (0.49) | PTGS2SRCBRAFKDRSMN1; SMN2 | |
| SCHEMBL28234718 | 0.78 | BRAF (0.70) | PTGS2SRCBRAFKDRSMN1; SMN2 | |
| SCHEMBL28624086 | 0.76 | SRC (0.53) | PTGS2SRCBRAFKDRSMN1; SMN2 | |
| SCHEMBL28624090 | 0.76 | SRC (0.55) | PTGS2SRCBRAFKDRSMN1; SMN2 | |
| SCHEMBL28616411 | 0.76 | SRC (0.53) | PTGS2SRCBRAFKDRSMN1; SMN2 | |
| SCHEMBL28233689 | 0.70 | LMNA (0.57) | PTGS2SMN1; SMN2NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409663-B | Microtubule inhibitors, methods of preparation and uses thereof | 成都威斯克生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |