Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 9/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21508490 | 0.90 | AAK1 (0.39) | LPLLIPGAAK1ROCK1EGFR | |
| SCHEMBL21508493 | 0.90 | AAK1 (0.39) | LPLLIPGAAK1ROCK1EGFR | |
| SCHEMBL15057082 | 0.89 | LPL (0.42) | LPLLIPGAAK1ROCK1ALDH1A1 | |
| SCHEMBL21918852 | 0.83 | AAK1 (0.41) | LPLLIPGAAK1ALDH1A1GAA | |
| SCHEMBL13466349 | 0.83 | ALDH1A1 (0.44) | LPLLIPGAAK1ALDH1A1GAA | |
| SCHEMBL142144 | 0.82 | LPL (0.49) | LPLLIPGROCK1EGFRCA1 | |
| SCHEMBL578320 | 0.82 | LPL (0.43) | LPLLIPGAAK1ROCK1EGFR | |
| SCHEMBL1328329 | 0.81 | LPL (0.45) | LPLLIPGAAK1ROCK1EGFR | |
| SCHEMBL1331278 | 0.81 | LPL (0.42) | LPLLIPGAAK1ROCK1EGFR | |
| SCHEMBL3192898 | 0.81 | LIPG (0.45) | LPLLIPGAAK1ROCK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674073-B | 3, 5-disubstituted-3H-imidazo [4,5-B ] pyridine compounds as modulators of protein kinases | 印蔻真治疗公司 | 2021-09-10 | — | — | CN | disclosed |