SCHEMBL29862373

SCHEMBL29862373

C[Si](C)(C)CCOCn1ccc(C#N)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.33
TBXAS1 P24557 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30478901 0.78
SCHEMBL28496046 0.78 DGAT1 (0.38) DGAT1
SCHEMBL28912548 0.76 DGAT1 (0.34) DGAT1
SCHEMBL10200583 0.76 DGAT1 (0.34) DGAT1
SCHEMBL16611601 0.76 DGAT1 (0.40) DGAT1
SCHEMBL30877301 0.76 DGAT1 (0.34) DGAT1
SCHEMBL28624418 0.76 DGAT1 (0.37) DGAT1
SCHEMBL3262382 0.75 DGAT1 (0.34) DGAT1
SCHEMBL28627973 0.74 DGAT1 (0.33) DGAT1
SCHEMBL1857202 0.73 DGAT1 (0.33) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313971-A1 SUBSTITUTED PYRROLE CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS Nerviano Medical Sciences S.r.l. (IT) 2024-02-07 EP disclosed
WO-2022207404-A1 SUBSTITUTED PYRROLE CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2022-10-06 WO disclosed