Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920788 | 0.68 | HTT (0.60) | SMN1; SMN2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL18413732 | 0.64 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28920802 | 0.63 | HTT (0.42) | SMN1; SMN2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL761369 | 0.63 | CDK4 (0.41) | RORCADORA2AADORA2BVCPALDH1A1 | |
| SCHEMBL17471423 | 0.61 | TSHR (0.38) | SMN1; SMN2ADORA2BADORA1ALDH1A1MEN1 | |
| SCHEMBL17243992 | 0.60 | MEN1 (0.38) | CYP3A4ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5558085 | 0.60 | ALDH1A1 (0.37) | RORCSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15964620 | 0.59 | KDM5B (0.40) | ADORA2AADORA2BADORA1 | |
| SCHEMBL15964621 | 0.58 | KDM5B (0.41) | ADORA2AADORA2BADORA1 | |
| SCHEMBL8467019 | 0.58 | ALDH1A1 (0.37) | RORCSMN1; SMN2VCPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166116-B | Amido bridged heterocyclic compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-113166116-A | Amido bridged heterocyclic compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2021-07-23 | — | — | CN | disclosed |