Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18413732 | 0.91 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1CYP2C19HCAR3 | |
| SCHEMBL17471423 | 0.88 | TSHR (0.38) | MEN1KMT2ATSHRALDH1A1HCAR3 | |
| SCHEMBL11376101 | 0.78 | TSHR (0.38) | MEN1KMT2ATSHRALDH1A1HCAR3 | |
| SCHEMBL23969200 | 0.65 | HSD11B1 (0.38) | KMT2AALDH1A1KDM4E | |
| SCHEMBL11843852 | 0.63 | HSD11B1 (0.37) | MEN1KMT2AALDH1A1CYP2C19KDM4E | |
| SCHEMBL8173050 | 0.62 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL18529420 | 0.61 | HSD11B1 (0.41) | KMT2ATSHRALDH1A1HTT | |
| SCHEMBL5082397 | 0.61 | ALDH1A1 (0.56) | KMT2AALDH1A1CYP2C19HTTCYP3A4 | |
| SCHEMBL21089365 | 0.61 | TSHR (0.37) | TSHRALDH1A1KDM4E | |
| SCHEMBL8924130 | 0.60 | HCAR3 (0.46) | CYP2C19HCAR3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181226-B2 | Benzamides | MERCK PATENT GMBH (DE) | 2015-11-10 | — | — | US | disclosed |