Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 6/20 | 0.32 |
| ▸ | RORB | Q92753 | 4/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552772 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10GAAKMT2A | |
| SCHEMBL9642917 | 0.79 | RAB9A (0.40) | ALDH1A1HPGDGAAKMT2AL3MBTL1 | |
| SCHEMBL5528292 | 0.78 | RORC (0.35) | GAAKMT2AL3MBTL1MEN1RORC | |
| SCHEMBL5553132 | 0.78 | KMT2A (0.48) | ALDH1A1HPGDGAAKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9528440 | 0.77 | RAB9A (0.39) | ALDH1A1HPGDGAAKMT2AL3MBTL1 | |
| SCHEMBL10266111 | 0.76 | L3MBTL1 (0.48) | ALDH1A1HPGDHSD17B10GAAKMT2A | |
| SCHEMBL5557908 | 0.75 | KMT2A (0.45) | ALDH1A1HPGDGAAKMT2AL3MBTL1 | |
| SCHEMBL9643713 | 0.74 | ALDH1A1 (0.34) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL9644276 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HPGDGAAKMT2AL3MBTL1 | |
| SCHEMBL5553553 | 0.74 | AGTR1 (0.34) | ALDH1A1HPGDGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | ALDH1A1 2042/4885HPGD 563/4885HSD17B10 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.