Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973389 | 0.78 | HTR6 (0.48) | SMN1; SMN2LMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL29848366 | 0.75 | NR4A2 (0.67) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A | |
| SCHEMBL20674165 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A | |
| SCHEMBL1887873 | 0.75 | NR4A2 (0.67) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A | |
| SCHEMBL20923997 | 0.74 | KMT2A (0.55) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A | |
| SCHEMBL4207590 | 0.74 | CREBBP (0.63) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A | |
| SCHEMBL15019983 | 0.72 | KMT2A (0.77) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A | |
| SCHEMBL14584176 | 0.72 | CREBBP (0.64) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A | |
| SCHEMBL8599833 | 0.72 | AKR1C3 (0.44) | SMN1; SMN2LMNAALDH1A1KMT2APOLB | |
| SCHEMBL12444946 | 0.71 | KAT2B (0.56) | SMN1; SMN2LMNACREBBPALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321640-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-09 | — | — | CN | disclosed |
| CN-109111427-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-02 | — | — | CN | disclosed |
| CN-113321640-A | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2021-08-31 | — | — | CN | disclosed |