SCHEMBL28624744

SCHEMBL28624744

C=CCc1c(/C=C/C(=O)OC)nnn1C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TP53 P04637 2/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PSMB8 P28062 1/20 0.33
PSMB9 P28065 1/20 0.33
PSMB5 P28074 1/20 0.33
S1PR1 P21453 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
KCNJ6 P48051 2/20 0.32
KCNJ5 P48544 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643458 1.00 ALDH1A1 (0.36) ALDH1A1MEN1KMT2ATP53USP2
SCHEMBL28638173 0.83 MEN1 (0.36) ALDH1A1MEN1KMT2ATP53USP2
SCHEMBL28635812 0.83 MEN1 (0.36) ALDH1A1MEN1KMT2ATP53USP2
SCHEMBL28621188 0.81 ALDH1A1 (0.41) ALDH1A1KMT2ATP53LMNATSHR
SCHEMBL28623306 0.81 ALDH1A1 (0.41) ALDH1A1KMT2ATP53LMNATSHR
SCHEMBL28623298 0.79 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATP53USP2
SCHEMBL28647500 0.79 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATP53USP2
SCHEMBL28646106 0.78 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ATP53USP2
SCHEMBL28628722 0.69 MEN1 (0.35) ALDH1A1MEN1KMT2ATP53USP2
SCHEMBL28633072 0.68 LMNA (0.33) ALDH1A1MEN1KMT2ATP53USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997231-B (E) Synthesis method of-configuration alkenyl ester triazole compound 陕西师范大学 2021-09-21 CN disclosed