SCHEMBL28624746

SCHEMBL28624746

NC(=O)c1ccccc1CC=Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.56
PTGER3 P43115 3/20 0.56
PTGER2 P43116 3/20 0.56
PAM P19021 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.48
MAPT P10636 5/20 0.45
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
MEN1 O00255 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
HTT P42858 1/20 0.41
MAOB P27338 1/20 0.41
GRIK1 P39086 2/20 0.41
GRIK2 Q13002 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3248765 0.86 PTGER4 (0.59) PTGER4PTGER3PTGER2PAMMAPT
SCHEMBL3248767 0.86 PTGER4 (0.59) PTGER4PTGER3PTGER2PAMMAPT
SCHEMBL7111348 0.86 PTGER4 (0.59) PTGER4PTGER3PTGER2PAMMAPT
SCHEMBL29004700 0.86 PTGER4 (0.59) PTGER4PTGER3PTGER2PAMMAPT
SCHEMBL7111345 0.86 PTGER4 (0.59) PTGER4PTGER3PTGER2PAMMAPT
SCHEMBL4101513 0.83 KDM4E (0.47) PTGER4PTGER3PTGER2SIRT2MAPT
SCHEMBL27432510 0.82 PTGER4 (0.55) PTGER4PTGER3PTGER2PAMMAPT
SCHEMBL6924561 0.81 ALDH1A1 (0.44) MAPTKDM4EALDH1A1LMNAHPGD
SCHEMBL4553805 0.81 KDM4E (0.44) MAPTKDM4EALDH1A1LMNAHPGD
SCHEMBL7197046 0.81 KDM4E (0.44) MAPTKDM4EALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699022-B Molecules having pesticidal utility, and intermediates, compositions and methods related to these molecules 美国陶氏益农公司 2021-11-09 CN disclosed
CN-109152363-B Molecules having pesticidal utility, and intermediates, compositions and methods related to these molecules 美国陶氏益农公司 2021-10-15 CN disclosed
CN-108882704-B Molecules having pesticidal utility, and intermediates, compositions and methods related to these molecules 美国陶氏益农公司 2021-09-10 CN disclosed
CN-108697091-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 美国陶氏益农公司 2021-07-23 CN disclosed