Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553805 | 0.85 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL7197046 | 0.85 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL7369716 | 0.85 | FOLH1 (0.50) | ALDH1A1KDM4EHPGDTSHRKMT2A | |
| SCHEMBL8930563 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL630666 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL28624746 | 0.81 | PTGER4 (0.56) | ALDH1A1KDM4EHPGDMAPTBCAT2 | |
| SCHEMBL28284541 | 0.80 | HTT (0.44) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL83923 | 0.79 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL630127 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL6336723 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EHPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260135-B | Synthesis method of oxindole compound | 浙江工业大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-115872920-A | Synthesis method of oxindole compound | 中国科学院大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-115260135-A | Synthesis method of oxindole compound | 浙江工业大学 | 2022-11-01 | — | — | CN | disclosed |
| WO-2004104009-A1 | PROCESS FOR MAKING SPIROLACTONE COMPOUNDS | MERCK & CO., INC. (US) | 2004-12-02 | — | — | WO | disclosed |