Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13542540 | 0.78 | GPR3 (0.52) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL20352857 | 0.76 | ACHE (0.42) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL2439142 | 0.75 | GPR3 (0.58) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL14584046 | 0.72 | GPR3 (0.46) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL29321 | 0.69 | GPR3 (1.00) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL29461528 | 0.69 | GPR3 (1.00) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL2758314 | 0.68 | HTR6 (0.45) | GPR3ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL24188661 | 0.68 | KDM4E (0.53) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL24188650 | 0.68 | KDM4E (0.53) | GPR3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL24188657 | 0.68 | GPR3 (0.44) | GPR3ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402553-B | Phosphine ligand of 2-alkyl-indole skeleton, preparation method and application thereof | 香港理工大学深圳研究院 | 2023-06-16 | — | — | CN | disclosed |
| CN-113402553-A | 2-alkyl-indole skeleton phosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2021-09-17 | — | — | CN | disclosed |