SCHEMBL28625413

SCHEMBL28625413

CN[C@H](CC(=O)OC)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
MGAM O43451 2/20 0.37
GAA P10253 2/20 0.37
SI P14410 2/20 0.37
MGAM2 Q2M2H8 2/20 0.37
HSD17B10 Q99714 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
BIRC2 Q13490 1/20 0.33
KMT2A Q03164 2/20 0.32
TET2 Q6N021 1/20 0.31
CA14 Q9ULX7 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1891853 1.00 TSHR (0.40) TSHRCA1CA2CA12CA9
SCHEMBL13033614 1.00 TSHR (0.40) TSHRCA1CA2CA12CA9
1,3,5-Trimethoxybenzene SCHEMBL27988479 0.86 KDM4E (0.45) CA1CA2CA12CA9GAA
SCHEMBL20022609 0.84 TSHR (0.42) TSHRCA1CA2CA12CA9
SCHEMBL13117955 0.82 CA12 (0.37) TSHRCA1CA2CA12MGAM
SCHEMBL19861713 0.82 TSHR (0.37) TSHRGAASMN1; SMN2BIRC2
SCHEMBL8580782 0.82 TSHR (0.40) TSHRCA1CA2CA12CA9
SCHEMBL10000227 0.82 ALDH1A1 (0.39) CA1CA2MGAMGAASI
SCHEMBL14268340 0.82 KMT2A (0.36) CA2HSD17B10SMN1; SMN2BIRC2KMT2A
SCHEMBL8580776 0.82 TSHR (0.40) TSHRCA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109628519-B Method for preparing N-methyl-D-aspartic acid by enzymatic resolution 江南大学 2021-08-24 CN disclosed