SCHEMBL28625846

SCHEMBL28625846

CNS(=O)(=O)c1ccc(N(c2ccc(N)cc2)[SH](=O)=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
GAA P10253 1/20 0.47
CA1 P00915 5/20 0.46
CA2 P00918 5/20 0.46
CA9 Q16790 5/20 0.46
CA12 O43570 4/20 0.46
CA3 P07451 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
CA7 P43166 2/20 0.46
CA13 Q8N1Q1 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
ALDH1A1 P00352 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687206 0.84 SMN1; SMN2 (0.64) SMN1; SMN2GAACA1CA2CA9
SCHEMBL31520571 0.84 SMN1; SMN2 (0.64) SMN1; SMN2GAACA1CA2CA9
Hydrochloric Acid SCHEMBL5344901 0.82 SMN1; SMN2 (0.61) SMN1; SMN2GAACA1CA2CA9
SCHEMBL11245748 0.74 SMN1; SMN2 (0.81) SMN1; SMN2GAACA1CA2CA9
SCHEMBL151299 0.74 CA1 (0.71) CA1CA2CA9ALDH1A1HTR6
SCHEMBL7629070 0.73 SMN1; SMN2 (0.80) SMN1; SMN2GAACA1CA2CA9
SCHEMBL27872854 0.72 CA9 (0.61) SMN1; SMN2GAACA1CA2CA9
SCHEMBL28872614 0.72 ACHE (0.56) SMN1; SMN2CA1CA2CA9CA12
SCHEMBL22800554 0.71 CA1 (0.55) SMN1; SMN2GAACA1CA2CA9
SCHEMBL30059765 0.69 ALDH1A1 (0.56) SMN1; SMN2GAAALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108349282-B Thermosensitive recording material and diphenyl sulfone 日本化药株式会社 2021-09-21 CN disclosed