Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | YES1 | P07947 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629173 | 0.91 | MAPT (0.44) | HSD17B1ESR2ESR1MAPTNPC1 | |
| SCHEMBL1071070 | 0.88 | ESR2 (0.51) | HSD17B1ESR2ESR1MAPTALDH1A1 | |
| SCHEMBL13730471 | 0.82 | CYP19A1 (0.49) | ESR2ESR1MAPTALDH1A1KDM4E | |
| SCHEMBL130268 | 0.82 | CYP19A1 (0.49) | ESR2ESR1MAPTALDH1A1KDM4E | |
| SCHEMBL3696621 | 0.80 | KDM4E (0.54) | ESR2ESR1MAPTALDH1A1KDM4E | |
| SCHEMBL28912178 | 0.79 | CA2 (0.43) | ESR2ESR1GABRA1GABRB2MAPT | |
| SCHEMBL28710319 | 0.77 | CYP19A1 (0.53) | MAPTALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL15453093 | 0.77 | CYP19A1 (0.50) | GABRA1GABRB2MAPTNPC1RAB9A | |
| SCHEMBL15453036 | 0.77 | PTPN1 (0.56) | GABRA1GABRB2CYP19A1PTPN1 | |
| SCHEMBL27639659 | 0.76 | ESR2 (0.51) | HSD17B1ESR2ESR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661738-B | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112661738-A | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2021-04-16 | — | — | CN | disclosed |