Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625919 | 0.91 | HSD17B1 (0.46) | MAPTNPC1RAB9AKDM4EHSD17B1 | |
| SCHEMBL2399209 | 0.77 | CA2 (0.45) | MAPTKDM4EPOLBALDH1A1LMNA | |
| SCHEMBL1071070 | 0.77 | ESR2 (0.51) | MAPTKDM4EHSD17B1AKR1B1ALDH1A1 | |
| SCHEMBL28912178 | 0.75 | CA2 (0.43) | MAPTKDM4EPOLBALDH1A1LMNA | |
| Acetic Acid SCHEMBL11666716 | 0.72 | KMT2A (0.43) | MAPTKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL28710319 | 0.72 | CYP19A1 (0.53) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL28635976 | 0.70 | KDM4E (0.32) | MAPTRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL1091431 | 0.70 | TDP1 (0.58) | MAPTNPC1RAB9AKDM4EHSD17B1 | |
| SCHEMBL10360806 | 0.69 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10360964 | 0.69 | MAOB (0.49) | AKR1B1ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661738-B | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112661738-A | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2021-04-16 | — | — | CN | disclosed |