Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459659 | 0.74 | CA1 (0.34) | CYP1A2CYP2C19TNFRSF1APTGS2ALDH1A1 | |
| SCHEMBL460486 | 0.72 | CA1 (0.43) | CYP1A2CYP2C19TNFRSF1AEGFRPTGS2 | |
| SCHEMBL2852821 | 0.71 | TNFRSF1A (0.38) | CYP1A2CYP2C19TNFRSF1AERBB2EGFR | |
| SCHEMBL458095 | 0.70 | ALDH1A1 (0.36) | CYP1A2TNFRSF1APTGS2ALDH1A1TSHR | |
| SCHEMBL1784097 | 0.69 | POLB (0.44) | CYP1A2CYP2C19NPSR1KMT2AMEN1 | |
| SCHEMBL14026094 | 0.67 | PTGS2 (0.38) | CYP1A2CYP2C19TNFRSF1APTGS2ALDH1A1 | |
| SCHEMBL5966327 | 0.67 | NPSR1 (0.53) | NPSR1KMT2AMEN1GAAMAPT | |
| SCHEMBL1304740 | 0.66 | PTGS2 (0.50) | CYP1A2TNFRSF1AERBB2EGFRPTGS2 | |
| SCHEMBL5384389 | 0.66 | CYP3A4 (0.39) | KMT2AMEN1ALDH1A1NQO2 | |
| SCHEMBL5090616 | 0.66 | CA2 (0.41) | TNFRSF1AERBB2EGFRPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318156-B1 | Novel asymmetric phosphine ligand | TAKASAGO PERFUMERY CO LTD (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-6730629-B2 | HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20030139285-A1 | Novel asymmetric phosphine ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1318156-A1 | Novel asymmetric phosphine ligand | Takasago International Corporation (JP) | 2003-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139285-A1 | Novel asymmetric phosphine ligand | PHOSPHO1, PAPSS1, PPM1F | CYP1A2 1910/4885CYP2C19 829/4885NPSR1 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.