Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722604 | 0.78 | MAOA (0.67) | MAOAMAOBNPC1RAB9ACYP1A2 | |
| SCHEMBL2852067 | 0.77 | PIP4K2C (0.51) | PIP4K2CMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL30373802 | 0.75 | MAOA (1.00) | MAOAMAOBNPC1RAB9ACYP1A2 | |
| SCHEMBL522503 | 0.75 | MAOA (1.00) | MAOAMAOBNPC1RAB9ACYP1A2 | |
| SCHEMBL3952305 | 0.75 | MAOA (0.67) | MAOAMAOBNPC1RAB9ACYP1A2 | |
| SCHEMBL7360499 | 0.75 | MAOA (0.67) | MAOAMAOBNPC1RAB9ACYP1A2 | |
| SCHEMBL7236728 | 0.75 | MAOA (0.69) | MAOAMAOBNPC1RAB9ACYP1A2 | |
| SCHEMBL2854358 | 0.74 | VNN1 (0.63) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL3715900 | 0.74 | CA12 (0.46) | ALDH1A1GAASMN1; SMN2ROCK1MEN1 | |
| Hydrochloric Acid SCHEMBL4509967 | 0.73 | MAOA (0.96) | MAOAMAOBNPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |