Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505232 | 0.80 | ALDH1A1 (0.39) | TUBB1ERN1ALDH1A1ORAI1CYP1A2 | |
| SCHEMBL3152062 | 0.79 | PRKDC (0.42) | TUBB1ERN1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL4497582 | 0.79 | TUBB1 (0.50) | TUBB1ERN1ALDH1A1TDP1 | |
| SCHEMBL24132612 | 0.78 | ALDH1A1 (0.38) | ERN1ALDH1A1CYP1A2TDP1BACE1 | |
| SCHEMBL28624223 | 0.78 | PRKDC (0.41) | TUBB1ERN1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL3222717 | 0.78 | ORAI1 (0.49) | ERN1ALDH1A1ORAI1CYP1A2KDM4E | |
| SCHEMBL31471572 | 0.78 | TDP1 (0.47) | TUBB1ERN1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL30664028 | 0.76 | LMNA (0.46) | TUBB1ERN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28613482 | 0.76 | LMNA (0.46) | TUBB1ERN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL31715172 | 0.75 | CYP1A2 (0.42) | ERN1ALDH1A1ORAI1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301959-A | Substituted chromen-4-ones for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-24 | — | — | CN | disclosed |