SCHEMBL28626734

SCHEMBL28626734

Cc1cc(C)c(C(C(=O)c2ccccc2)S(=O)(=O)S(=O)(=O)S(=O)(=O)C(C(=O)c2ccccc2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
METAP2 P50579 1/20 0.38
FFAR4 Q5NUL3 1/20 0.37
LMNA P02545 3/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
RAB9A P51151 1/20 0.36
MAPT P10636 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28559895 0.88 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3L3MBTL1METAP2
SCHEMBL28626733 0.82 LMNA (0.38) SLC6A2SLC6A4SLC6A3L3MBTL1METAP2
SCHEMBL28382673 0.79 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3L3MBTL1METAP2
SCHEMBL5999756 0.76 CES2 (0.53) SLC6A2SLC6A4SLC6A3L3MBTL1LMNA
SCHEMBL4809206 0.76 PGR (0.46) SLC6A2SLC6A4SLC6A3L3MBTL1LMNA
SCHEMBL7543173 0.76 CES2 (0.44) SLC6A2SLC6A4SLC6A3L3MBTL1LMNA
SCHEMBL7542397 0.74 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3L3MBTL1LMNA
SCHEMBL29130635 0.74 CES2 (0.52) SLC6A2SLC6A4SLC6A3L3MBTL1LMNA
SCHEMBL7542392 0.74 LMNA (0.42) SLC6A2SLC6A4SLC6A3L3MBTL1LMNA
SCHEMBL28559893 0.72 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113448167-A Photosensitive resin composition 味之素株式会社 2021-09-28 CN disclosed