SCHEMBL28627043

SCHEMBL28627043

CC1CC(C)(c2ccc(Cl)cc2)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 1/20 0.41
TP53 P04637 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
KDM1A O60341 1/20 0.36
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4582810 0.86 SIGMAR1 (0.47) CCR2ALDH1A1MAPTSIGMAR1MAOA
SCHEMBL28615808 0.80 SIGMAR1 (0.40) CCR2TP53SMN1; SMN2SIGMAR1
SCHEMBL11797794 0.80 ALDH1A1 (0.39) TP53ALDH1A1MAPTKDM1A
SCHEMBL28615619 0.77 KDM1A (0.43) SIGMAR1KDM1A
SCHEMBL23795250 0.73 TP53 (0.52) CCR2TP53SMN1; SMN2MAPTTHRB
SCHEMBL11796945 0.71 SIGMAR1 (0.46) CCR2TP53ALDH1A1MAPTSIGMAR1
SCHEMBL2139658 0.71 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1MAPT
SCHEMBL30027759 0.71 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1MAPT
SCHEMBL29415514 0.71 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1MAPT
SCHEMBL23795253 0.70 TP53 (0.54) CCR2TP53SMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113365976-A Diphenylindane, triphenylindane and tetraphenylindan derivatives and their use in organic devices 多蒂肯独家合成控股公司 2021-09-07 CN disclosed