SCHEMBL28627683

SCHEMBL28627683

C#Cc1ccc(C(=O)C=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 1/20 0.52
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
PTPN1 P18031 1/20 0.36
PKM P14618 2/20 0.35
HTT P42858 2/20 0.35
ATM Q13315 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 1/20 0.35
NLRP1 Q9C000 1/20 0.35
MEN1 O00255 1/20 0.35
NTSR1 P30989 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222221 0.81 ALDH1A1 (0.74) ALDH1A1TDP1MAPK1PKMHTT
Water SCHEMBL10349944 0.78 CA2 (0.57) ALDH1A1TDP1MAPK1CA1CA2
SCHEMBL1673513 0.78 CA2 (0.57) ALDH1A1TDP1MAPK1CA1CA2
Water SCHEMBL11592742 0.78 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1PKMHTT
Water SCHEMBL11592745 0.78 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1PKMHTT
SCHEMBL13582530 0.77 CES2 (0.48) CA1CA2CA12CA4CA9
SCHEMBL3838955 0.77 SRD5A2 (0.48) ALDH1A1MAPK1CA1CA2CA12
Formic Acid SCHEMBL28150588 0.76 CA12 (0.46) CA1CA2CA12CA4CA9
SCHEMBL28615735 0.75 ALDH1A1 (0.65) ALDH1A1TDP1MAPK1
Formic Acid SCHEMBL28050738 0.75 PARP10 (0.44) ALDH1A1TDP1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113382987-B AIE compounds with fluorescent, photoacoustic and Raman properties 香港科技大学 2023-09-01 CN disclosed
CN-113382987-A AIE compounds with fluorescent, photoacoustic and Raman properties 香港科技大学 2021-09-10 CN disclosed