SCHEMBL28627864

SCHEMBL28627864

CC(CC(=O)O)C(=O)OCCO

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.33
ACHE P22303 1/20 0.33
CACNA2D1 P54289 2/20 0.32
CACNB3 P54284 1/20 0.32
CACNA1C Q13936 1/20 0.32
PGR P06401 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
CACNA2D2 Q9NY47 1/20 0.32
CYP1A2 P05177 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
REN P00797 1/20 0.32
ACE P12821 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28276784 0.88 MEN1 (0.41) TSHRALDH1A1
SCHEMBL12085235 0.86 ACHE (0.39) ACHE
SCHEMBL7598967 0.83 HCAR2 (0.41) TSHRALDH1A1SLC22A6TDP1SMN1; SMN2
SCHEMBL13168078 0.83 SLC22A6 (0.33) SLC22A6CACNA2D1CACNB3CACNA1CPGR
SCHEMBL14417127 0.83 TSHR (0.35) TSHRALDH1A1ACHEADRA1A
SCHEMBL4111791 0.79 ALDH1A1 (0.48) TSHRALDH1A1TDP1SMN1; SMN2
SCHEMBL28217966 0.78 NAAA (0.47) TSHRALDH1A1
SCHEMBL12132240 0.77 CYP2C19 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL786190 0.77 ACHE (0.39) TSHRALDH1A1ACHE
SCHEMBL13876695 0.77 ACHE (0.39) TSHRALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110078902-B Method for synthesizing glycol polyester plasticizer 镇江巨杰新材料技术研发中心(有限合伙) 2021-09-24 CN disclosed