Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Resveratrol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA3 | P07451 | 3/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.61 |
| ▸ | CA6 | P23280 | 3/20 | 0.61 |
| ▸ | CA5A | P35218 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.61 |
| ▸ | TTR | P02766 | 3/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resveratrol SCHEMBL19022423 | 0.95 | PTGS2 (0.68) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL19331480 | 0.86 | PTGS2 (0.70) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL27883730 | 0.83 | PTGS2 (0.76) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL28719858 | 0.82 | PTGS2 (0.83) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL30291837 | 0.80 | PTGS2 (0.66) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL28030055 | 0.79 | PTGS2 (0.76) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL29473334 | 0.79 | PTGS2 (0.76) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL21225662 | 0.79 | PTGS2 (0.76) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL28307179 | 0.78 | KDM4E (0.91) | PTGS2CYP1A1PTGS1CYP1A2KDM4E | |
| Resveratrol SCHEMBL20164915 | 0.78 | PTGS1 (1.00) | PTGS2CYP1A1PTGS1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181370-A | Synthesis process of tumor targeting drug | 六安市康恒生物科技有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113181370-A | Synthesis process of tumor targeting drug | 六安市康恒生物科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-113181370-A | Synthesis process of tumor targeting drug | 六安市康恒生物科技有限公司 | 2021-07-30 | — | — | CN | disclosed |