Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Resveratrol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CA12 | O43570 | 3/20 | 0.68 |
| ▸ | CA1 | P00915 | 3/20 | 0.68 |
| ▸ | CA2 | P00918 | 3/20 | 0.68 |
| ▸ | CA3 | P07451 | 3/20 | 0.68 |
| ▸ | CA4 | P22748 | 3/20 | 0.68 |
| ▸ | CA6 | P23280 | 3/20 | 0.68 |
| ▸ | CA5A | P35218 | 3/20 | 0.68 |
| ▸ | CA7 | P43166 | 3/20 | 0.68 |
| ▸ | CA9 | Q16790 | 3/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.68 |
| ▸ | TTR | P02766 | 3/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resveratrol SCHEMBL28627984 | 0.95 | PTGS2 (0.61) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL19331480 | 0.87 | PTGS2 (0.70) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL27883730 | 0.87 | PTGS2 (0.76) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL28719858 | 0.87 | PTGS2 (0.83) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL30291837 | 0.84 | PTGS2 (0.66) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL29473334 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL28030055 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL21225662 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Resveratrol SCHEMBL28307179 | 0.82 | KDM4E (0.91) | PTGS2PTGS1CYP1A1CYP1A2KDM4E | |
| Cis-Resveratrol SCHEMBL1931746 | 0.82 | PTGS1 (1.00) | PTGS2PTGS1CYP1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190241498-A1 | RESVERATROL ESTERS | COLE RES & DESIGN LLC (US) | 2019-08-08 | — | — | US | claimed |
| US-20170183290-A1 | RESVERATROL ESTERS | COLE RESEARCH & DESIGN, LLC. | 2017-06-29 | — | — | US | claimed |
| US-20190241498-A1 | RESVERATROL ESTERS | COLE RES & DESIGN LLC (US) | 2019-08-08 | — | — | US | disclosed |
| CN-104256295-B | The vegetarian diet powder and preparation method thereof of plant phenols glycinate phytic acid salt composite stability maintenance | 宁波御坊堂生物科技有限公司 | 2019-06-21 | — | — | CN | disclosed |
| US-10099995-B2 | Resveratrol esters | Cole Research and Design, LLC (US) | 2018-10-16 | — | — | US | disclosed |
| WO-2018164662-A1 | RESVERATROL ESTERS | ELSOHLY MAHMOUD A (US) | 2018-09-13 | — | — | WO | disclosed |
| US-20170183290-A1 | RESVERATROL ESTERS | COLE RESEARCH & DESIGN, LLC. | 2017-06-29 | — | — | US | disclosed |
| CN-104256295-A | Vegetarian powder capable of keeping stability by utilizing plant phenolic glycine ester phytate composition and preparation method thereof | NINGBO YUFANGTANG BIOTECHNOLOGY CO LTD | 2015-01-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241498-A1 | RESVERATROL ESTERS | HCAR1, HCAR3, HCAR2 | PTGS2 3131/4885PTGS1 2487/4885CYP1A1 460/4885 |
| US-20170183290-A1 | RESVERATROL ESTERS | HCAR1, HCAR3, HCAR2 | PTGS2 3131/4885PTGS1 2487/4885CYP1A1 460/4885 |
| US-10099995-B2 | Resveratrol esters | HCAR1, HCAR3, HCAR2 | PTGS2 3131/4885PTGS1 2487/4885CYP1A1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.