Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 4/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23777354 | 0.85 | TP53 (0.47) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL8660951 | 0.84 | SLC6A11 (0.45) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL13575117 | 0.84 | SLC6A11 (0.45) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL31003057 | 0.84 | SLC6A11 (0.45) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL4066783 | 0.84 | SLC6A11 (0.51) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL31511279 | 0.83 | KIF11 (0.40) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL6839724 | 0.83 | SLC6A11 (0.50) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL13575115 | 0.82 | SLC6A11 (0.46) | SLC6A11SLC6A1KIF11TP53MEN1 | |
| SCHEMBL7090463 | 0.82 | KIF11 (0.60) | SLC6A11SLC6A1KIF11KCNH2 | |
| SCHEMBL2385290 | 0.82 | SLC6A11 (0.46) | SLC6A11SLC6A1KIF11TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365662-A | Method of treatment | 盖纳万科学有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-113226332-A | Bivalent targeting conjugates | 阿布特斯生物制药公司 | 2021-08-06 | — | — | CN | disclosed |