Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471666 | 0.93 | RORC (0.43) | HRH3POLBPDE4DPDE4APDE4B | |
| SCHEMBL30780930 | 0.82 | POLB (0.42) | POLBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL14454144 | 0.79 | GPR6 (0.45) | RORCGPR6 | |
| SCHEMBL12195758 | 0.77 | POLB (0.64) | POLBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL26989922 | 0.77 | HRH2 (0.36) | HRH3 | |
| SCHEMBL22069550 | 0.76 | HRH3 (0.52) | HRH3POLBPDE4DPDE4APDE4B | |
| SCHEMBL13105587 | 0.75 | NPY1R (0.45) | POLBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL10188238 | 0.75 | CSNK2A1 (0.41) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5881031 | 0.75 | FPR2 (0.47) | — | |
| SCHEMBL22114120 | 0.75 | SYK (0.48) | PDE4DPDE4APDE4BPDE4CGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677723-B | 5-HT2A receptor antagonists and their use for treating central nervous system disorders | 瀚远医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115677723-A | 5-HT2A receptor antagonists and their use for the treatment of central nervous system disorders | 瀚远医药有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113214289-B | 5-HT2A receptor antagonists and their use for the treatment of central nervous system disorders | 瀚远医药有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-113214289-A | 5-HT2A receptor antagonists and their use for the treatment of central nervous system disorders | 瀚远医药有限公司 | 2021-08-06 | — | — | CN | disclosed |