Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628239 | 0.82 | HRH3 (0.42) | POLBRORCPDE4APDE4BPDE4C | |
| SCHEMBL28331542 | 0.79 | EIF4E (0.43) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12195758 | 0.79 | POLB (0.64) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15057752 | 0.77 | MRGPRX1 (0.43) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL13105587 | 0.76 | NPY1R (0.45) | POLBRORCPDE4APDE4BPDE4C | |
| SCHEMBL14471667 | 0.75 | RORC (0.66) | POLBRORCCSNK2A1 | |
| SCHEMBL14471666 | 0.75 | RORC (0.43) | POLBRORCPDE4APDE4BPDE4C | |
| SCHEMBL28954258 | 0.75 | RORC (0.37) | RORCPDE4D | |
| SCHEMBL29951339 | 0.74 | RORC (0.43) | POLBRORCPDE4APDE4BPDE4C | |
| SCHEMBL29953879 | 0.74 | ALDH1A1 (0.42) | POLBRORCPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |