Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857833 | 0.82 | TDP1 (0.57) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL689735 | 0.81 | VCAM1 (0.66) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL21121958 | 0.80 | XDH (0.51) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL29980060 | 0.79 | ALDH1A1 (0.60) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL4645678 | 0.79 | ALDH1A1 (0.56) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL23648373 | 0.79 | ALDH1A1 (0.60) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| Nitrogen SCHEMBL28796067 | 0.79 | VCAM1 (0.64) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL3218901 | 0.79 | VCAM1 (0.46) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL3874387 | 0.79 | ALDH1A1 (0.56) | TDP1ALDH1A1TSHRGAATHRB | |
| SCHEMBL15461632 | 0.78 | VCAM1 (0.62) | TDP1ALDH1A1TSHRGAAVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619880-A | Low-cost and environment-friendly method for preparing 4-hydroxyquinoline-2 (1H) -ketone compound | 浙江外国语学院 | 2024-09-10 | — | — | CN | disclosed |
| CN-117384201-A | 1-alkenyl indole compound and preparation method thereof | 鲁东大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-113416166-B | Method for preparing 4-hydroxyquinoline-2 (1H) -ketone compound | 浙江外国语学院 | 2022-08-05 | — | — | CN | disclosed |
| CN-113416166-A | Method for preparing 4-hydroxyquinoline-2 (1H) -ketone compound | 浙江外国语学院 | 2021-09-21 | — | — | CN | disclosed |