SCHEMBL28628490

SCHEMBL28628490

CS(=O)(=O)NP(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.45
LMNA P02545 1/20 0.41
PGR P06401 1/20 0.40
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
NR3C2 P08235 3/20 0.39
KMT2A Q03164 2/20 0.38
POLB P06746 3/20 0.38
APOBEC3A P31941 1/20 0.38
CASP6 P55212 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
ESR1 P03372 1/20 0.38
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGS2 P35354 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21693345 0.77 MEN1 (0.48) KEAP1LMNAPGRCA2KMT2A
SCHEMBL18535398 0.74 CA2 (0.39) LMNACA2CA4CA5AKMT2A
SCHEMBL9617518 0.72 CA2 (0.52) LMNACA2CA4CA5AKMT2A
SCHEMBL13109422 0.71 CA2 (0.50) LMNACA2CA4CA5AESR1
SCHEMBL524346 0.71 CA2 (0.50) LMNACA2CA4CA5AKMT2A
SCHEMBL30604627 0.69 CA2 (0.48) LMNACA2CA4CA5AESR1
Potassium SCHEMBL30627046 0.69 CA2 (0.48) LMNACA2CA4CA5AESR1
Triphenylphosphine Oxide SCHEMBL8328973 0.67 CA2 (0.52) LMNACA2CA4CA5AKMT2A
SCHEMBL27300024 0.67 CA2 (0.46) LMNACA2CA4CA5AKMT2A
SCHEMBL647195 0.67 CA2 (0.52) LMNACA2CA4CA5AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474333-B Novel substituted sulphones ureide derivatives 载度思生命科学有限公司 2025-06-13 CN disclosed
CN-113474333-A Novel substituted sulfonylurea derivatives 卡迪拉保健有限公司 2021-10-01 CN disclosed