Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428351 | 0.79 | CA2 (0.46) | CA2CA4CA5ALMNAESR1 | |
| SCHEMBL524346 | 0.78 | CA2 (0.50) | CA2CA4CA5ALMNAESR1 | |
| SCHEMBL13109422 | 0.78 | CA2 (0.50) | CA2CA4CA5ALMNAESR1 | |
| Potassium SCHEMBL30627046 | 0.76 | CA2 (0.48) | CA2CA4CA5ALMNAESR1 | |
| SCHEMBL30604627 | 0.76 | CA2 (0.48) | CA2CA4CA5ALMNAESR1 | |
| SCHEMBL524587 | 0.74 | CA2 (0.46) | CA2CA4CA5ALMNAESR1 | |
| SCHEMBL647195 | 0.74 | CA2 (0.52) | CA2CA4CA5ALMNAESR1 | |
| SCHEMBL27300024 | 0.74 | CA2 (0.46) | CA2CA4CA5ALMNAESR1 | |
| Triphenylphosphine Oxide SCHEMBL3949 | 0.74 | CA2 (0.58) | CA2CA4CA5ALMNAESR1 | |
| Triphenylphosphine Oxide SCHEMBL513223 | 0.74 | CA2 (0.58) | CA2CA4CA5ALMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4247093-A | — | — | None | — | — | JP | disclosed |
| US-8748369-B2 | Use of targeted nitroxide agents in bone healing | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748369-B2 | Use of targeted nitroxide agents in bone healing | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120252733-A1 | USE OF TARGETED NITROXIDE AGENTS IN BONE HEALING | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120252733-A1 | USE OF TARGETED NITROXIDE AGENTS IN BONE HEALING | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-10-04 | — | — | US | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| JP-H04247093-A | PHOSPHINIC ACID AMIDE DERIVATIBE AND FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE | HOKKO CHEM IND CO LTD | 1992-09-03 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252733-A1 | USE OF TARGETED NITROXIDE AGENTS IN BONE HEALING | NME4, TFAM, COX5B | CA2 1880/4885CA4 3498/4885CA5A 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.