SCHEMBL647195

SCHEMBL647195

O=P(NO)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA5A P35218 1/20 0.52
CFTR P13569 1/20 0.46
ALOX15 P16050 2/20 0.43
GAA P10253 2/20 0.43
TSHR P16473 2/20 0.43
USP2 O75604 1/20 0.43
ESR1 P03372 1/20 0.43
HDAC3 O15379 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
IDO1 P14902 1/20 0.42
HDAC1 Q13547 1/20 0.42
CA9 Q16790 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL29126721 0.97 CA2 (0.50) CA2CA4CA5ACFTRALOX15
SCHEMBL524346 0.78 CA2 (0.50) CA2CA4CA5ACFTRALOX15
SCHEMBL13109422 0.78 CA2 (0.50) CA2CA4CA5ACFTRALOX15
Triphenylphosphine Oxide SCHEMBL8431247 0.77 CA2 (0.63) CA2CA4CA5ACFTRALOX15
Triphenylphosphine Oxide SCHEMBL8431251 0.77 CA2 (0.63) CA2CA4CA5ACFTRALOX15
SCHEMBL30604627 0.76 CA2 (0.48) CA2CA4CA5ACFTRALOX15
Potassium SCHEMBL30627046 0.76 CA2 (0.48) CA2CA4CA5ACFTRALOX15
SCHEMBL9617518 0.74 CA2 (0.52) CA2CA4CA5ACFTRGAA
SCHEMBL27300024 0.74 CA2 (0.46) CA2CA4CA5ACFTRALOX15
SCHEMBL524587 0.74 CA2 (0.46) CA2CA4CA5ACFTRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241622-B 3′-ONH2Synthesis method of ribonucleotide 凯莱英生命科学技术(天津)有限公司 2025-04-18 CN claimed
CN-119241622-A 3′-ONH2Synthesis method of ribonucleotide 凯莱英生命科学技术(天津)有限公司 2025-01-03 CN claimed
CN-118344239-A Method for efficiently constructing carbon-carbon bond by nitrogen deletion reaction 南京大学 2024-07-16 CN claimed
CN-115353184-B Surface modified chitosan-agar flocculant and preparation method and application thereof 湖南仁和环境股份有限公司 2024-01-26 CN claimed
CN-113620274-A Method for preparing lignin-based carbon quantum dots with high quantum yield quickly, simply and conveniently 广东工业大学 2021-11-09 CN claimed
CN-112552339-A Preparation method of O-diphenylphosphoryl hydroxylamine 安徽昊帆生物有限公司 2021-03-26 CN claimed
CN-108047156-B 5-methylmorpholine-3-amino-2-oxazolidinyl ketone antigen with spiro structure, antibody, preparation and application 华南农业大学 2020-08-07 CN claimed
EP-1931341-B1 1H-INDOLE-PYRIDINECARBOXAMIDE AND 1H-INDOLE-PIPERIDINECARBOXAMIDE DERIVATIVES AND THEIR USE AS TYROSINE HYDROXYLASE INDUCERS SERVIER LAB (FR) 2009-11-04 EP claimed
WO-2006127368-A2 METHODS FOR SYNTHESIZING IMIDAZOTRIAZINONES LEXICON GENETICS INCORPORATED (US) 2006-11-30 WO claimed
CN-122071464-A Heterocyclic compound, pharmaceutical composition thereof and application thereof 上海璎黎药业有限公司 2026-05-22 CN disclosed
US-20260132136-A1 Pyrazolo[5,1-f][1,2,4]triazin-4-ones as inhibitors of NOX4 BOEHRINGER INGELHEIM INT GMBH (DE) 2026-05-14 US disclosed
US-12624044-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-05-12 US disclosed
CN-122000468-A High-temperature-resistant electrolyte and lithium ion battery 国网湖南省电力有限公司防灾减灾中心 2026-05-08 CN disclosed
EP-4313980-B1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC (CA) 2026-04-22 EP disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 WO disclosed
US-4956470-A BACTERICIDES, FUNGICIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS HOFFMANN-LA ROCHE INC. (US) 1990-09-11 US disclosed
EP-0353902-A1 Substituted phenyltriazolopyrimidine herbicides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-02-07 EP disclosed
US-4831151-A NEMATOCIDES HOFFMANN-LA ROCHE INC. (US) 1989-05-16 US disclosed
US-4814332-A PARASITICIDES HOFFMAN-LA ROCHE INC. (US) 1989-03-21 US disclosed
US-4808727-A CHEMICAL INTERMEDIATES FOR WATER-SOLUBLE SALTS OF PARASITICIDES HOFFMANN-LAROCHE INC. (US) 1989-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132136-A1 Pyrazolo[5,1-f][1,2,4]triazin-4-ones as inhibitors of NOX4 NOX4, NOX1, NOX3 CA2 937/4885CA4 2248/4885CA5A 317/4885
US-12624044-B2 SMARCA degraders and uses thereof SMARCA1, SMARCC1, SMARCA2 CA2 2413/4885CA4 2933/4885CA5A 3808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.