Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967105 | 0.86 | TP53 (0.57) | L3MBTL1MAPTTP53ACRHPGD | |
| SCHEMBL5620616 | 0.85 | MAPT (0.72) | MAPTTP53HPGDKDM4EALDH1A1 | |
| SCHEMBL1686476 | 0.85 | MAPT (0.72) | L3MBTL1MAPTTP53ACRTHRB | |
| SCHEMBL768649 | 0.85 | ACR (0.63) | L3MBTL1MAPTTP53ACRHPGD | |
| SCHEMBL2967428 | 0.84 | L3MBTL1 (0.55) | L3MBTL1MAPTTP53ACRHPGD | |
| SCHEMBL1227407 | 0.84 | L3MBTL1 (0.73) | L3MBTL1MAPTTP53ACRHPGD | |
| SCHEMBL5620054 | 0.84 | SMN1; SMN2 (0.56) | L3MBTL1MAPTTP53ACRHPGD | |
| SCHEMBL210302 | 0.84 | TRPM8 (0.55) | L3MBTL1MAPTTP53ACRHPGD | |
| SCHEMBL2108368 | 0.81 | MAPT (0.57) | L3MBTL1MAPTTP53ACRHPGD | |
| SCHEMBL29775668 | 0.81 | MAPT (0.57) | L3MBTL1MAPTTP53ACRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307779-B | Heterocyclic substituted biphenyl compound, preparation method and application | 中国药科大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-113307779-A | Heterocyclic substituted biphenyl compound, preparation method and application | 中国药科大学 | 2021-08-27 | — | — | CN | disclosed |