SCHEMBL28629039

SCHEMBL28629039

COC(=O)c1[c]c(/C=C\I)ccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 2/20 0.39
TSHR P16473 2/20 0.36
POLB P06746 2/20 0.33
LMNA P02545 1/20 0.33
HCRTR1 O43613 1/20 0.33
HCRTR2 O43614 1/20 0.33
CA5A P35218 1/20 0.33
ALDH1A1 P00352 3/20 0.33
CFTR P13569 1/20 0.33
HSD17B10 Q99714 1/20 0.33
P4HB P07237 2/20 0.32
LOXL2 Q9Y4K0 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127720 0.84 CA1 (0.52) CA1CA2CA9CA12CA7
SCHEMBL27847162 0.75 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL9195826 0.73 CA1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL8026225 0.73 CA1 (0.45) CA1CA2CA9CA12CA7
SCHEMBL27387454 0.72 CA1 (0.41) CA1CA2CA9CA12CA7
SCHEMBL27556890 0.72 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL4390548 0.72 CA1 (0.44) CA1CA2CA9CA12CA7
SCHEMBL3891739 0.72 CA12 (0.44) CA1CA2CA9CA12CA7
SCHEMBL7260462 0.69 L3MBTL1 (0.42) CA1CA2CA9CA12CA7
SCHEMBL27397465 0.68 LOXL2 (0.47) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107847617-B Metal tricarbonyl complexes containing substituted iminodiacetic acid ligands and their use as radiotracers 爱默蕾大学 2021-08-31 CN disclosed