SCHEMBL28629167

SCHEMBL28629167

CCOC(=NO)c1ccc(C=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
CYP2A6 P11509 2/20 0.41
ALDH3A1 P30838 1/20 0.39
ALDH1A3 P47895 1/20 0.39
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP3 Q9Y6F1 1/20 0.38
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA7 P43166 2/20 0.37
CA9 Q16790 2/20 0.37
CA14 Q9ULX7 2/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
ALDH5A1 P51649 1/20 0.36
ABAT P80404 1/20 0.36
MAPT P10636 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361965 0.78 ESR1 (0.55) ALDH1A1ADRB1ADRB3CA12CA1
SCHEMBL528212 0.77 CA1 (0.63) ALDH1A1ADRB2ADRB1ADRB3CA12
SCHEMBL7930050 0.76 KDM4E (0.38) ALDH1A1CA12CA1CA2CA7
SCHEMBL6920338 0.76 MEN1 (0.44) ALDH1A1MAPTNPC1RAB9ALMNA
SCHEMBL25218257 0.75 ALDH1A1 (0.47) ALDH1A1CYP2A6ALDH3A1ALDH1A3ADRB2
SCHEMBL9939035 0.75 DGAT1 (0.49) ALDH1A1CYP2A6ALDH3A1ALDH1A3ADRB2
Hydrochloric Acid SCHEMBL9939515 0.74 DGAT1 (0.47) ALDH1A1CYP2A6ALDH3A1ALDH1A3ADRB2
SCHEMBL29017437 0.74 ALDH1A1 (0.50) ALDH1A1CYP2A6ALDH3A1ALDH1A3ADRB2
SCHEMBL1537537 0.72 NPC1 (0.60) ALDH1A1ADRB2ADRB1ADRB3CA12
SCHEMBL10702293 0.72 CA12 (0.58) ALDH1A1ADRB2ADRB1ADRB3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912414-B Preparation method and application of 4-formaldehyde oxime ethyl benzoate 荆门医药工业技术研究院 2021-09-17 CN claimed
CN-109912414-B Preparation method and application of 4-formaldehyde oxime ethyl benzoate 荆门医药工业技术研究院 2021-09-17 CN disclosed
CN-109912414-B Preparation method and application of 4-formaldehyde oxime ethyl benzoate 荆门医药工业技术研究院 2021-09-17 CN disclosed
CN-109912414-B Preparation method and application of 4-formaldehyde oxime ethyl benzoate 荆门医药工业技术研究院 2021-09-17 CN disclosed