Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361965 | 0.82 | ESR1 (0.55) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL13273168 | 0.82 | MEN1 (0.43) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL10075193 | 0.82 | MEN1 (0.43) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL10694796 | 0.81 | TSHR (0.47) | MAPTNPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11207345 | 0.79 | AKR1C3 (0.49) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL28170963 | 0.79 | RAB9A (0.60) | MEN1KMT2AMAPTALDH1A1ATM | |
| SCHEMBL27849629 | 0.79 | TSHR (0.46) | KMT2AMAPTSMN1; SMN2ATMLMNA | |
| SCHEMBL6820105 | 0.78 | LMNA (0.50) | MAPTNPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28863986 | 0.78 | TDP1 (0.55) | KMT2AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22208244 | 0.77 | MEN1 (0.47) | MEN1KMT2AMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067518-A1 | SUBSTITUTED PYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-12 | — | — | WO | disclosed |
| EP-0647217-B1 | 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES | ZENECA LTD (GB) | 1997-10-29 | — | — | EP | disclosed |
| EP-0334863-B1 | PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES | AlliedSignal Inc. (US) | 1992-04-15 | — | — | EP | disclosed |
| EP-0334863-A1 | PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES. | ALLIED CORP (US) | 1989-10-04 | — | — | EP | disclosed |
| WO-1988004291-A1 | PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES | ALLIED CORPORATION (US) | 1988-06-16 | — | — | WO | disclosed |
| US-4743701-A | Process for the preparation of organo N-hydroxyimidates | ALLIED CORPORATION (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0035291-B1 | PROCESS FOR CARRYING OUT RADICAL REACTIONS AND SHAPED ARTICLES OF THE REACTION PRODUCT | AKZO N.V. (NL) | 1983-05-11 | — | — | EP | disclosed |
| US-4374938-A | HYDROXIMIC ACID DERIVATIVE AS FREE RADICAL INITIATOR | AKZONA INCORPORATED (US) | 1983-02-22 | — | — | US | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |
| EP-0035291-A1 | Process for carrying out radical reactions and shaped articles of the reaction product | AKZO N.V. (NL) | 1981-09-09 | — | — | EP | disclosed |