Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22119499 | 1.00 | DDB1 (0.58) | DDB1CRBNNAMPTMAPTKDM4E | |
| SCHEMBL23538658 | 0.92 | DDB1 (0.69) | DDB1CRBNNAMPTMAPTKDM4E | |
| SCHEMBL28638009 | 0.88 | DDB1 (0.64) | DDB1CRBNNAMPTMAPTKDM4E | |
| SCHEMBL22119702 | 0.88 | DDB1 (0.64) | DDB1CRBNNAMPTMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL29946980 | 0.87 | DDB1 (0.63) | DDB1CRBNNAMPT | |
| SCHEMBL22119482 | 0.85 | DDB1 (0.44) | DDB1CRBNMAPTNPC1RAB9A | |
| SCHEMBL25631901 | 0.85 | DDB1 (0.60) | DDB1CRBNNAMPTALOX12JAK2 | |
| SCHEMBL22144678 | 0.82 | DDB1 (0.47) | DDB1CRBNJAK2JAK3PTK2 | |
| SCHEMBL25631947 | 0.81 | DDB1 (0.56) | DDB1CRBNALOX12 | |
| SCHEMBL30257373 | 0.81 | DDB1 (0.62) | DDB1CRBNMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015338-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| US-12454521-B2 | Targeted protein degradation | C4 THERAPEUTICS, INC. | 2025-10-28 | — | — | US | disclosed |
| US-20220372016-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2022-11-24 | — | — | US | disclosed |
| CN-113453679-A | Targeted protein degradation | C4医药公司 | 2021-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015338-A1 | TARGETED PROTEIN DEGRADATION | PSMC3, PSMA6, ADRM1 | DDB1 716/4885CRBN 17/4885NAMPT 4868/4885 |
| US-20220372016-A1 | TARGETED PROTEIN DEGRADATION | STUB1, MDM2, UBE3A | DDB1 219/4885CRBN 55/4885NAMPT 3483/4885 |
| US-12454521-B2 | Targeted protein degradation | STUB1, MDM2, UBE3A | DDB1 219/4885CRBN 55/4885NAMPT 3483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.