Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | GCGR | P47871 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627575 | 0.86 | ALDH1A1 (0.41) | MAPK14GCGRALDH1A1MAPTMAPK13 | |
| SCHEMBL28195670 | 0.86 | KIF11 (0.51) | MAPK14GCGRALDH1A1MAPTCA12 | |
| SCHEMBL28646815 | 0.82 | MAPT (0.47) | MAPK14GCGRALDH1A1MAPTGAA | |
| SCHEMBL28195069 | 0.82 | MAPT (0.47) | MAPK14GCGRALDH1A1MAPTGAA | |
| SCHEMBL28641174 | 0.82 | ALDH1A1 (0.47) | MAPK14GCGRALDH1A1MAPTGAA | |
| SCHEMBL31126425 | 0.82 | MAPT (0.47) | MAPK14GCGRALDH1A1MAPTGAA | |
| SCHEMBL31126418 | 0.81 | ALDH1A1 (0.46) | MAPK14GCGRALDH1A1MAPTGAA | |
| SCHEMBL31126426 | 0.81 | ALDH1A1 (0.46) | MAPK14GCGRALDH1A1MAPTGAA | |
| SCHEMBL28195676 | 0.80 | MAPT (0.45) | MAPK14GCGRALDH1A1MAPTGAA | |
| SCHEMBL28627861 | 0.78 | GCGR (0.47) | MAPK14GCGRALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-107625766-B | Application of thiazole compound as antibacterial synergist | 上海医药工业研究院 | 2021-08-31 | — | — | CN | disclosed |