SCHEMBL28630437

SCHEMBL28630437

CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2sccc2Br)CC1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 14/20 0.51
F13A1 P00488 11/20 0.51
TGM1 P22735 8/20 0.51
TGM3 Q08188 1/20 0.47
GPR119 Q8TDV5 2/20 0.44
PKM P14618 1/20 0.44
POLB P06746 1/20 0.43
STS P08842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16781 0.78 PKM (0.71) PKMPOLB
SCHEMBL710366 0.77 TGM2 (0.64) TGM2F13A1TGM1PKM
SCHEMBL1348953 0.77 POLB (0.72) TGM2F13A1TGM1PKMPOLB
SCHEMBL10042199 0.76 EPHX2 (0.53) TGM2F13A1TGM1TGM3GPR119
SCHEMBL2376710 0.75 ABL1 (0.59) TGM2F13A1TGM1
SCHEMBL27200534 0.74 TGM2 (0.64) TGM2F13A1TGM1GPR119PKM
SCHEMBL2512179 0.74 TGM2 (0.55) TGM2F13A1TGM1TGM3GPR119
SCHEMBL6977155 0.74 TGM2 (0.62) TGM2F13A1TGM1PKM
SCHEMBL2252120 0.74 TGM2 (0.63) TGM2F13A1TGM1GPR119
SCHEMBL31165481 0.74 TGM2 (0.56) TGM2F13A1TGM1GPR119PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384764-B Phenyl thiophene sulfonamide compound, pharmaceutical composition, preparation method and application thereof 中国科学院上海有机化学研究所 2021-09-03 CN disclosed