Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627669 | 0.82 | MEN1 (0.58) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL19306397 | 0.81 | KMT2A (0.78) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL28626118 | 0.80 | HTR7 (0.66) | MEN1KMT2AHTR7LMNA | |
| SCHEMBL19306513 | 0.80 | MEN1 (0.71) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL28629819 | 0.78 | HTR7 (0.67) | MEN1KMT2AMAPTHTR7LMNA | |
| SCHEMBL28636511 | 0.76 | HTR7 (0.61) | MEN1KMT2AHTR7 | |
| SCHEMBL28638514 | 0.72 | HTR7 (0.67) | MEN1KMT2AHTR7 | |
| SCHEMBL28626494 | 0.72 | HTR7 (0.63) | MEN1KMT2AHTR7 | |
| SCHEMBL5151681 | 0.71 | MEN1 (0.59) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL19305954 | 0.71 | MEN1 (0.81) | MEN1KMT2AMAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |