Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.37 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 5/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630594 | 1.00 | SLC28A1 (0.37) | SLC28A1SLC28A2SLC29A1SLC28A3KDM5A | |
| SCHEMBL22119700 | 0.91 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL30087102 | 0.81 | HCAR1 (0.51) | — | |
| SCHEMBL13968 | 0.81 | HCAR1 (0.51) | — | |
| SCHEMBL26916149 | 0.76 | CRBN (0.47) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL8334 | 0.75 | ALDH1A1 (0.46) | PNPRAMP1CALCRL | |
| SCHEMBL28640716 | 0.75 | HCAR1 (0.58) | CRBNDDB1L3MBTL1 | |
| SCHEMBL28541089 | 0.75 | KDM5A (0.54) | KDM5AL3MBTL3L3MBTL1 | |
| SCHEMBL12062407 | 0.73 | HCAR1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL4112401 | 0.72 | HCAR1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453679-A | Targeted protein degradation | C4医药公司 | 2021-09-28 | — | — | CN | disclosed |