Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193 | 0.82 | SRC (0.44) | ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL28630594 | 0.75 | SLC28A1 (0.37) | PNPCALCRLRAMP1 | |
| SCHEMBL28630591 | 0.75 | SLC28A1 (0.37) | PNPCALCRLRAMP1 | |
| SCHEMBL12062409 | 0.75 | ALDH1A1 (0.60) | ALDH1A1POLBKMT2ASMN1; SMN2TK1 | |
| SCHEMBL19513999 | 0.72 | KDM5A (0.42) | ALDH1A1POLBKMT2ASMN1; SMN2GAA | |
| SCHEMBL28539787 | 0.72 | KDM5A (0.42) | ALDH1A1POLBKMT2ASMN1; SMN2GAA | |
| SCHEMBL3250125 | 0.69 | DRD2 (0.37) | KMT2ACALCRLTNKSDRD2DRD4 | |
| SCHEMBL3246969 | 0.69 | CALCRL (0.45) | CALCRLTNKSDRD2DRD4DRD3 | |
| SCHEMBL2099353 | 0.68 | DRD2 (0.65) | CALCRLTNKSDRD2DRD4DRD3 | |
| SCHEMBL28541089 | 0.67 | KDM5A (0.54) | ALDH1A1KMT2ASMN1; SMN2TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488525-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Rib-X Pharmaceuticals, Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |