SCHEMBL2864790

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2871126	0.86	KDR (0.50)	CDK2CDK4CCNA2CCND1CCND3
	SCHEMBL2861482	0.81	CDK4 (0.48)	CDK2CDK4CCNA2CCND1CCND3
	SCHEMBL13636075	0.80	CDK4 (0.47)	CDK2CDK4CCNA2CCND1CCND3
	SCHEMBL13635731	0.80	CDK4 (0.50)	CDK2CDK4CCNA2CCND1CCND3
	SCHEMBL2863072	0.80	TTK (0.47)	TTKTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL2864750	0.78	CDK2 (0.43)	CDK2CDK4CCNA2CCND1CCND3
	SCHEMBL2865609	0.78	CDK4 (0.46)	CDK2CDK4CCNA2CCND1CCND3
	SCHEMBL6545434	0.78	CDK4 (0.45)	CDK2CDK4CCNA2CCND1CCND3
	SCHEMBL2858841	0.77	TUBB4A (0.42)	KDRTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL2861862	0.77	TUBB4A (0.42)	MAPKAPK2TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.