Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473562 | 0.89 | PDE4B (0.56) | PKMKDM4EGPR119PDE4APDE4B | |
| SCHEMBL30015882 | 0.89 | PDE4B (0.56) | PKMKDM4EGPR119PDE4APDE4B | |
| SCHEMBL1056543 | 0.89 | PDE4B (0.54) | PKMKDM4EGPR119PDE4APDE4B | |
| SCHEMBL23825806 | 0.86 | RBP4 (0.41) | PKMKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL19834162 | 0.86 | KDM4E (0.47) | PKMKDM4EGPR119PDE4APDE4B | |
| SCHEMBL29366131 | 0.85 | HTR4 (0.40) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27392260 | 0.85 | HDAC1 (0.50) | PKMKDM4EGPR119HDAC1SLC2A1 | |
| SCHEMBL31160608 | 0.84 | GPR119 (0.49) | PKMKDM4EGPR119PDE4APDE4B | |
| SCHEMBL2802032 | 0.83 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL241130 | 0.83 | GPR119 (0.59) | PKMKDM4EGPR119HDAC1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302184-A | 1,3, 4-oxadiazolinone compounds and drugs | 日本新药株式会社 | 2021-08-24 | — | — | CN | disclosed |