Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912507 | 0.86 | TDP1 (0.51) | ALDH1A1MAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL3886138 | 0.84 | KDM4E (0.49) | ALDH1A1MAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL30798461 | 0.84 | TDP1 (0.53) | ALDH1A1MAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL4074618 | 0.84 | TDP1 (0.53) | ALDH1A1MAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL6017355 | 0.82 | TDP1 (0.54) | ALDH1A1TDP1L3MBTL1PKMMAP2K1 | |
| SCHEMBL9694170 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL17714455 | 0.81 | TDP1 (0.50) | ALDH1A1MAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL4556786 | 0.81 | TDP1 (0.53) | ALDH1A1TDP1L3MBTL1PKMMAP2K1 | |
| SCHEMBL29361610 | 0.81 | TDP1 (0.53) | ALDH1A1TDP1L3MBTL1PKMMAP2K1 | |
| SCHEMBL16790454 | 0.80 | TDP1 (0.51) | ALDH1A1TDP1L3MBTL1PKMMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316568-A | 2-formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2021-08-27 | — | — | CN | disclosed |