SCHEMBL28630968

SCHEMBL28630968

Cc1ccc(-c2ccnc(-c3ccc(Br)cc3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TGFBR1 P36897 1/20 0.46
PIK3CA P42336 1/20 0.43
PIK3CG P48736 1/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
KDM4E B2RXH2 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
KDM1A O60341 3/20 0.43
HDAC1 Q13547 3/20 0.43
HDAC6 Q9UBN7 1/20 0.43
APP P05067 1/20 0.42
PAX8 Q06710 1/20 0.42
MAP4K4 O95819 1/20 0.42
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28660538 1.00 ALDH1A1 (0.46) ALDH1A1TGFBR1PIK3CAPIK3CGNPC1
SCHEMBL28132456 0.91 MAP4K4 (0.47) ALDH1A1PIK3CAPIK3CGNPC1RAB9A
SCHEMBL15506226 0.91 TGFBR1 (0.51) ALDH1A1TGFBR1NPC1RAB9AKDM4E
SCHEMBL12339160 0.85 NPC1 (0.50) ALDH1A1TGFBR1NPC1RAB9AKDM4E
SCHEMBL12339139 0.85 NPC1 (0.50) ALDH1A1TGFBR1NPC1RAB9AKDM4E
SCHEMBL16242385 0.85 CCR1 (0.56) TGFBR1LMNAMAPTMAP4K4CCR1
SCHEMBL11978726 0.84 MEN1 (0.56) ALDH1A1TGFBR1NPC1RAB9AKDM4E
SCHEMBL12339171 0.84 MEN1 (0.56) ALDH1A1TGFBR1NPC1RAB9AKDM4E
SCHEMBL18572778 0.84 ALDH1A1 (0.56) ALDH1A1TGFBR1PIK3CANPC1RAB9A
SCHEMBL5956691 0.83 CCR1 (0.61) ALDH1A1PIK3CAPIK3CGNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113461914-B D-pi-A type polymer fluorescent material containing 2, 6-diphenyl-4-aryl pyridine structure and synthetic method thereof 上饶师范学院 2022-05-10 CN disclosed
CN-113461914-A D-pi-A type polymer fluorescent material containing 2, 6-diphenyl-4-aryl pyridine structure and synthetic method thereof 上饶师范学院 2021-10-01 CN disclosed