Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.61 |
| ▸ | CCR5 | P51681 | 1/20 | 0.61 |
| ▸ | CCR8 | P51685 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31695263 | 0.89 | CCR1 (0.76) | CCR1CCR5CCR8CYP2A6NPC1 | |
| SCHEMBL27344644 | 0.89 | CCR1 (0.76) | CCR1CCR5CCR8CYP2A6NPC1 | |
| SCHEMBL29463685 | 0.85 | CCR1 (0.70) | CCR1CCR5CCR8CYP2A6NPC1 | |
| SCHEMBL6807225 | 0.85 | CCR1 (0.70) | CCR1CCR5CCR8CYP2A6NPC1 | |
| SCHEMBL28660538 | 0.83 | ALDH1A1 (0.46) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL28630968 | 0.83 | ALDH1A1 (0.46) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16210551 | 0.81 | MEN1 (0.47) | NPC1RAB9AKDM4EPIK3CAPIK3CG | |
| SCHEMBL5699981 | 0.80 | KDM1A (0.46) | CCR1CCR5CCR8CYP2A6NPC1 | |
| SCHEMBL2190158 | 0.80 | CYP2A6 (0.62) | CCR1CCR5CCR8CYP2A6NPC1 | |
| SCHEMBL6183900 | 0.80 | CCR1 (0.61) | CCR1CCR5CCR8CYP2A6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467412-A | A kind of green-yellow light phenylpyridine complex of iridium and its preparation method and application | 南京邮电大学 | 2018-08-31 | — | — | CN | claimed |
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |
| CN-108467412-A | A kind of green-yellow light phenylpyridine complex of iridium and its preparation method and application | 南京邮电大学 | 2018-08-31 | — | — | CN | disclosed |
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| CN-103958471-B | Anthracene derivant and use its organic electric field luminescence assembly, electron transport material, display device and lighting device | 捷恩智株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-103958471-A | Anthracene derivative and organic electroluminescent element using same | JNC CORP | 2014-07-30 | — | — | CN | disclosed |
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | DODIC NERINA | 2005-11-03 | — | — | US | disclosed |
| EP-1554275-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004013134-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | SMAD2, SMAD3, ALK | CCR1 1244/4885CCR5 327/4885CCR8 1108/4885 |
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | CCR1 1707/4885CCR5 263/4885CCR8 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.